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항암화학요법을 받은 유방암환자의 무월경 발생과 갱년기 증상 관련요인

 Factors of Occurrence of Amenorrhea and Climacteric Symptoms in Breast Cancer Patients Underwent Chemotherapy

여성건강간호학회지 2008년 14권 3호 p.189 ~ 195
KMID : 0606420080140030189
장순복 ( Chang Soon-Bok ) - 연세대학교 간호대학

이경희 ( Lee Kyung-Hi ) - 세브란스병원 유방센터 코디네이터
정재원 ( Chung Chae-Weon ) - 서울대학교 간호대학

Abstract

Purpose:This study aimed to investigate the factors of occurrence of amenorrhea and the severity of climacteric symptoms in breast cancer patients who underwent chemotherapy.

Method:Women diagnosed with breast cancer without metastasis or recurrence, had surgery followed by chemotherapy, and hadmenses at the time of surgery were recruited from S hospital located in Seoul. A total of 99 women aged 31 thru 55 years participated and filled out a structured questionnaire including the Functional Assessment Cancer Therapy-Breast plus Endocrine Symptom when they visited the clinic for follow-up.

Result:In 88 women amenorrhea occurred within an average of 2 months since beginning chemotherapy, and menstruation was resumed in only 11 women. About 98% of women aged over 40 experienced a cessation in menses thus age was an apparent factor of amenorrhea (Exp(B)=.76, p<.05). Presence of chronic disease (ß=.25, p<.05) and body weight change (ß=.30, p<.01) were significant factors influencing the severity of climacteric symptoms.

Conclusion:Nurses need to have clinical evidences of menstrual changes due to breast cancer treatment. Information about premature menopause and climacteric symptoms should be provided according to women’s health conditions so that they cope better during their survival.
KeyWords

Breast cancer, Chemotherapy, Amenorrhea, Climacteric
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학술진흥재단(KCI) KoreaMed